Risks and evidence
The tier tells you how well a compound has been studied. It is not a safety rating and not a recommendation. A well-characterised drug can still hurt you, that is precisely what its label warnings are for. An uncharacterised one can hurt you in ways nobody has documented yet.
Approved by at least one major regulator for a defined indication, with published human pharmacokinetics and a prescribing label. Well-characterised does not mean risk-free, read the label warnings.
Studied in registered human trials with published pharmacokinetic data, but not approved. Dosing outside a trial protocol has no established safety margin.
Evidence is limited to animal or in-vitro work. No human pharmacokinetics. Any human dose in circulation is extrapolated, and extrapolation across species routinely fails.
Either documented serious adverse events in humans, or effectively no retrievable evidence base. Dosing figures circulating for these compounds have no scientific foundation.
What this app does not know
Of 74 compounds in the library, 21 have a half-life traceable to a real source and 53 do not. That second number is not a gap we intend to quietly fill, for several of these compounds, no human pharmacokinetic study has ever been published, and any specific figure you find elsewhere was invented somewhere along the chain.
Where a study exists only in rats or dogs, we say so and refuse to extrapolate. Peptide pharmacokinetics routinely fail to translate across species, and a number that looks precise is more dangerous than an honest blank.
Where dosing in the published trials was weight-based (mcg per kilogram), we keep it that way rather than back-calculate a fixed dose from an assumed body weight. That conversion would be a guess wearing the costume of a fact.
Things that are true regardless of tier
- Product identity is unverified. Material sold as a research peptide has no regulated manufacturing standard. What is in the vial may not be what is on the label, at the purity claimed, or sterile. Several compounds here are commonly sold under a name that belongs to a different molecule.
- Absence of reported harm is not safety. For compounds nobody has systematically studied in humans, there is no adverse-event record because nobody kept one, not because nothing happened.
- Legality varies and is your responsibility. Many of these are unlawful to sell for human use, and most are prohibited in sport at all times.