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N-Acetyl Semax Amidate

Nootropic

Also known as: NA Semax Amidate, NASA, Ac-MEHFPGP-NH2, N-acetyl semax amidate

Tier 4, Documented harm or no usable evidence

Either documented serious adverse events in humans, or effectively no retrievable evidence base. Dosing figures circulating for these compounds have no scientific foundation.

Half-life
Not established

No primary pharmacokinetic study located for the acetylated/amidated analog. Vendor claims of an 'extended half-life' (e.g. '~30 min longer than Semax' or '2-10 h') are extrapolations from the known chemistry (N-acetylation blocks aminopeptidases, C-amidation blocks carboxypeptidases) and are NOT backed by a measured PK study, treat as unverified.

Dosing
No established dose

No primary-sourced dose. This is a research-chemical variant with no clinical registration; all dosing guidance is vendor/community-derived. Typically used intranasally.

Regulatory status
Not approved by any regulator. Sold only as a research chemical. Distinct modified analog, the Russian Semax registration does NOT cover this compound.
Evidence base
none found · confidence: low

No peer-reviewed PK or efficacy studies found for the acetylated-amidated form specifically. Human data absent; mechanistic claims are inferred from parent Semax.

Storage

Lyophilised: General peptide convention: -20 C lyophilized (no compound-specific data).

Reconstituted: General convention: 2-8 C refrigerated (no compound-specific data).

Safety

Unstudied modified analog; no safety data. Longer duration is theoretical, which could also prolong any adverse effects. Not for human use per regulators.