5-Amino-1MQ
Small-molecule NNMT inhibitor
Also known as: 5-amino-1-methylquinolinium, 5-amino-1-methylquinolinium iodide
Evidence is limited to animal or in-vitro work. No human pharmacokinetics. Any human dose in circulation is extrapolated, and extrapolation across species routinely fails.
No human or animal half-life located in an allowed primary source. MW 159.21 is the 5-amino-1-methylquinolinium cation (PubChem); the research material is commonly the iodide salt (higher formula weight).
Dosed by body weight in mice: ~20 mg/kg subcutaneously three times daily in diet-induced obese mouse studies. Kept as mg/kg per instructions; no back-calculation. No established human dose.
Rodent obesity/metabolic studies only; no human data. Evidence overwhelmingly preclinical.
No human safety data. Preclinical only; safety in humans is unestablished. Not for clinical dosing decisions.